Stiftelsen lantbruksforskning

Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
Läs mer

Sykdomskontroll og forbedret dyrevelferd ved hjelp av genetiske markører: En pilotstudie av osteochondrose og Birkelandfraktur hos hest

Status: Avslutat
Projektnummer: H1247154
Kategori: Research program | Horse
Ansökningsår: 2012
Datum för slutrapport: 30 september 2018
Huvudsökande: Gunnar Klemetsdal
Organisation: Universitetet for miljø og biovitenskap (UMB)
E-postadress: Gunnar.Klemetsdal@umb.no
Telefon: ?
Medsökande: Nils Ivar Dolvik
Medsökande: Sigrid Lykkjen

The project aims to verify our current findings of QTLs with effect on osteochondrosis and Birkelandfracture in the Standarbred trotter. The project triples the sizes of the groups in the genome-wise association studies. The project will serve a basis for international involvement, either to identidy QTLs or in genomic selection.

Prosjektets mål er å verifiserer våre nåværende funn av QTLer med effect på osteochondrose og Birkelandfraktur hos varmblodstraver. Prosjektet tredobler størrelsen på forsøksgruppene i de genom-vide assosiasjonsstudiene. Prosjektet vil også være et springbrett for å komme inn i internasjonalt sammarbeid, enten for å finne QTLer, eller i genomisk seleksjon.

Ett mål i prosjektet var å verifisere QTL funnene som tidligere er rapportert av Lykkjen og medarbeidere på osteokondrose og Birkelandfraktur på varmblodstraver. Ved å øke materialet betydelig falt mange QTL bort, og bare en QTL på kromosom 28 var signifikant. En vil nå søke å tilnærme det mulige underliggende genet ved å utnytte kandidatgener. Med bare ett signifikant QTL funn, bør fremtidig forskning på OCD og POF ikke bare rettes inn mot å utnytte noe av genetisk varians ved å fokusere en QTL tilnærming, men heller ved å utnytte en mye større andel av genetisk variasjon gjennom genetisk seleksjon. Hos hest bør dette gjennomføres over populasjon av travere, men også inkludere data på varmblods ridehest. Relevante data vil i store trekk finnes i forskjellige forskningsprosjekt. Et slikt over-populasjons initiativ på OCD kan sees på som en modell for andre sykdommer, og andre arter, som heller ikke har etablert sykdomsregistering.

Osteochondrosis dissecans (OCD) and Birkelandfracture, are diseases mainly in the hock and fetlock joints of varmblooded horses, respectively, that increase the costs in the horse industry and affect animal welfare negatively, since many horses have to be operated. The diseases contribute to increased costs for treatment and restitution, reduced performance and income as well as reduced value of the animal itself. High frequencies of the diseases illustrate the importance of revealing the causative nature of OCD and POF.

Selection can be used as a preventive means towards such diseases, either on the quantitative trait loci (QTL) itself or on estimated breeding values, by summing the effect of all alleles into a genomic breeding value. The project aimed at verifying QTL findings that have been reported by Lykkjen and coworkers for OCD and POF in the Standardbred trotter. By considerably increasing the size of the material of Lykkjen and coworkers, only the finding of a QTL on chromosome 28 still held promise as a QTL. Our approach now is to use the candidate gene approach to possibly reveal the underlying causative gene. With only one QTL left to consider, this indicates that future research towards improving the genetics of OCD and POF should be approached by not only utilizing some of the genetic variance through a QTL approach, but rather to utilize more of the genetic variance through genomic selection, across populations of trotter, but also including data from riding horse populations. Such data will in main be available through research projects. Such an across-population initiative on OCD can be considered a model for other diseases, as well, and even for other species that do not either have a disease recording system in place.

In the same material, we also estimated the effect of inbreeding on racing performance. The effect was negative, i.e. that racing performance in Standardbred trotters is concluded depressed by inbreeding In corollary, crossbreeding is encouraged, and is one explanation of the recently increased contribution of French trotter in the Norwegian population of Standardbreds.

 

Antal träffar i projektbanken: 1647

Automatiska registreringar för ökad djurhälsa och djurvälfärd hos betesdjur
Mats Emilson, Agroväst Livsmedel AB

Projektnummer: R-18-62-992 • Status: Avslutat • Datum för slutrapport: 31 januari 2020

Global livestock production must be intensified to meet the demand from a growing human population. However, this must not be at the expense of reduced animal health and deteriorated animal welfare. Infection with parasitic worms of ruminants is a major constraint on an efficient pasture-based …

Läs mer

Frihet från smittsamma sjukdomar hos nöt - vägen till bättre hälsa, produktion och resistensläge
Björn Bengtsson,

Projektnummer: O-15-20-330 • Status: Avslutat • Datum för slutrapport: 17 januari 2020

Kött
Mjölk

This project investigates the impact of infections with bovine respiratory syncytial virus (BRSV) and bovine corona virus (BCV) in dairy herds on overall disease burden in the herd, usage of antibiotics, prevalence of antibiotic resistances and herd productivity. The aim is to document the …

Läs mer

Test av belastningsfördelning på underlag med olika mjukhetsgrad och spaltöppningar för nötkreatur
Evgenij Telezhenko

Projektnummer: O-16-20-781 • Status: Avslutat • Datum för slutrapport: 31 december 2019

Kött
Mjölk

The purpose of the project is to measure pressure distribution of cattle claws on solid and slatted floors with varying softness and slot openings. The aim is to produce recommendations for the design of floors for cattle that better meet animal welfare requirements. Floor tests will be made using …

Läs mer

Hur stödjer vi bäst implementering av innovationer i lantbruket - exemplet Yara N-sensor
Magnus Ljung

Projektnummer: O-16-21-763 • Status: Pågående • Ansökningsår: 2016

Växtodling

The aim of this project is to take different actors perspectives in describing the process through which Yara N-sensor went from a decision support system used by a few early adopters to a well-known sensor used by extension services and authorities as a base for fertilisation recommendations …

Läs mer

Utvärdering av differentierade somatiska celler som verktyg för förbättrad juverhälsoutvärdering.
Fredrik Westerberg, Eurofins Steins Laboratorium

Projektnummer: R-18-26-012 • Status: Avslutat • Datum för slutrapport: 27 december 2019

Swedish milk needs to be more internationally competitive. To achieve this objective costs related to production need to decrease at the same time as customer perceived values are strengthened and more clearly communicated. Lowering the incidence of mastitis reduces the production cost for farmers. …

Läs mer

Långsiktig fosforförsörjning från mark - utvärdering av P-AL och betydelsen av stabila fosforformer
Jon Petter Gustafsson,

Projektnummer: O-15-23-311 • Status: Pågående • Ansökningsår: 2015

Växtodling

In Sweden, fertilization recommendations are based on results obtained from the P-AL (ammonium lactate) soil test, which is supposed to provide the potentially available phosphorus (P). There are known deficiencies with this method, for example that it is poorly suited to determine the availability …

Läs mer

Ny teknik för grobarhetsbedömning av spannmål
Thomas Börjesson

Projektnummer: O-15-20-576 • Status: Avslutat • Datum för slutrapport: 20 december 2019

Växtodling

In this project we intend to study different methods to objectively monitor the germination of seeds. In the project we will both study cereal seeds and malting barley. The methods that we intend to compare are isothermal calorimetry and two image analysis systems. One of the systems is well …

Läs mer

Ridundervisningens pedagogiska praktik; lärande, interaktion och kommunikation om ryttarkänsla
Anna Bergh, SLU

Projektnummer: H-15-47-054 • Status: Avslutat • Datum för slutrapport: 20 december 2019

The aim of the project is to study how instructors at Swedish riding schools instruct and communicate "the riding feeling". The focus is on communication, pupil´s learning and the interaction between instructor, pupil and horse. The "riding feeling" is a tacit knowledge and refers to the rider’s …

Läs mer

Spridningsvägar och prognos för Acrothecium-röta i lagrade morötter
Mariann Wikström

Projektnummer: O-15-20-578 • Status: Pågående • Ansökningsår: 2015

Trädgård
Växtodling

The purpose of this project is to clarify the source of infection and spread of Acrothecium carotae - the pathogen that causes a serious rot on stored carrots. We have to know the epidemiology of the pathogen in order to effectively control this serious disease. The project has four goals; to …

Läs mer

Riskfaktorer för sjuklighet hos kalvar i den specialiserade köttproduktionen samt möjligheter till profylax.
Stefan Alenius, Sveriges Lantbruksuniversitet - SLU

Projektnummer: V1350026 • Status: Avslutat • Datum för slutrapport: 31 oktober 2019

Pneumonia is the most prevalent disease in Swedish feedlot cattle herds, causing mortality as well as affecting weight gain, rearing time and economy. Viral infections, including bovine respiratory syncytial virus (BRSV) and bovine coronavirus (BCV) as major actors, cause respiratory disease. …

Läs mer

Prenumerera på vårt nyhetsbrev

Namn
E-postadress