Stiftelsen lantbruksforskning

Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
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Anatomisk besrkivelse av den nevro-sentrale synchondrosen: strukturen som kan forklare cervical vertebral stenotisk myelopati ("wobbler") på unge hester

Status: Pågående
Projektnummer: H-20-47-553
Kategori: Research program | Horse
Ansökningsår: 2020
Huvudsökande: Kristin Olstad
Organisation: Norwegian University of Life Sciences, Faculty of Veterinary Medicine
E-postadress: kristin.olstad@nmbu.no
Telefon: +4793231969
Medsökande: Anne Selvén Kallerud
Medsökande: Bjørnar Ytrehus
Beviljade medel: 342 000 SEK

Young horses can develop cervical vertebral stenotic myelopathy and ataxia, known as "wobbler syndrome" and associated with loss of breeding value, reduced athletic potential and euthanasia. Some wobblers have osteochondrosis of their vertebral facet joints, but it is now known how this relates to the narrowing of the spinal canal seen in wobblers. During research in pigs, a structure known as the neuro-central synchondrosis was discovered. The ends of it are responsible for forming the facet joints, and the middle is responsible for forming the spinal canal. The neuro-central synchondrosis is not described in textbooks of veterinary anatomy. The aim of the project is therefore to generate an anatomical description of the neuro-central synchondrosis in the neck of foals, using diagnostic imaging. The description will form the basis for future diagnosis of disease in this structure, with the potential to explain narrowing of the spinal canal and wobbler syndrome in young horses.

Unge hester kan utvikle cervikal vertebral stenotisk myelopati og ataksi, kjent som «wobbler syndrom» og forbundet med tap av avlsverdi, nedsatt atletisk potensial og eutanasi. Noen wobblere har osteochondrose i sine vertebrale fasettledd, men det er ikke kjent hvordan dette henger sammen forsnevringen av ryggmargskanalen i wobbler syndrom. Under forskning på gris ble det oppdaget en struktur kjent som den nevro-sentrale synchondrosen. Endene av strukturen er ansvarlige for å danne fasettleddene, og midten er ansvarlig for å danne ryggmargskanalen. Den nevro-sentrale synchondrosen er ikke beskrevet i tekstbøker for veterinæranatomi. Målet med prosjektet er derfor å lage en anatomisk beskrivelse av den nevro-sentrale synchondrosen i nakken på føll, gjennom bruk av avansert billeddiagnostikk. Beskrivelsen vil legge grunnlaget for fremtidig diagnose av sykdom i denne strukturen, med potensial til å forklare forsnevring av ryggmargskanalen og wobbler syndrom på unge hester.

 

Antal träffar i projektbanken: 1676

Identifiering av gener med negativ inverkan på hästens hälsa och välbefinnande: Ett ramverk baserat på helgenomsekvensering och bioinformatik på häst
Sofia Mikko, Sveriges lantbruksuniversitet

Projektnummer: H-18-47-406 • Status: Pågående • Ansökningsår: 2018

The overall aim of this project is to improve equine health and welfare by identifying causative mutations for inherited diseases to aid informed breeding of healthy horses. We will use a comparative genomics approach, combining whole-genome sequencing (WGS) and bioinformatics with state-of-the-art …

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Finns 'Hopparknä' hos häst?- en studie av patellardesmopati som orsak till knähälta hos sporthästar
Marie Rhodin, Sveriges Lantbruksuniversitet

Projektnummer: H-18-47-393 • Status: Pågående • Ansökningsår: 2018

Soft tissues around the kneecap (patella) as a cause of equine lameness is an area yet to be scientifically investigated but that is often clinically treated with “alternative” methods without an established diagnosis. In human medicine, patellar tendinosis is a common verified diagnosis. …

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Störd glukagonmetabolism - en direkt orsak till hyperinsulinemi och fång hos häst?
Johan Bröjer, SLU

Projektnummer: H-18-47-390 • Status: Pågående • Ansökningsår: 2018

Laminitis, an extremely painful disease of the equine foot, is most commonly caused by elevated insulin
concentrations in blood (hyperinsulinemia). Therefore, strategies to reduce hyperinsulinemia in horses are warranted.
Studies in obese children with insulin dysregulation and hyperinsulinemia …

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En mänsklig sida av hästvälfärden
Petra Andersson, Göteborgs universitet

Projektnummer: H-18-47-401 • Status: Pågående • Ansökningsår: 2018

The goal of the applied project is to shed light on overlooked aspects of the complex subject of horse welfare.
Because of the specific position stall owners have, they are especially suitable to contribute to our knowledge about
the possibilities and limitations that set the conditions for …

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Blodtilførselen til vekstbrusken i glideleddene, med relevans for utviklingssykdommer og spatt
Kristin Olstad, Norges miljø- og biovitenskapelige universitet

Projektnummer: H-16-47-192 • Status: Pågående • Ansökningsår: 2016

The current project has a basic science and a clinical relevance part. The main project aim is to describe the blood supply to the growth cartilage of the small tarsal bones in young Icelandic Horses. Similar studies of the blood supply to long bones that ossify from three separate centers have …

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Hest i trafikk
Eva Brustad Dalland, Nord universitet

Projektnummer: H-17-47-302 • Status: Pågående • Ansökningsår: 2017

Horse in traffic is a qualitative case study that aims to provide knowledge about interactions between horse, horse users and modern road traffic, and which type of measures might be needed to improve road safety. Providing knowledge about typical events and situations for equestrians and horse …

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Rasmus Bovbjerg Jensen, NMBU - Norges miljø- og biovitenskapelige universitet

Projektnummer: H-17-47-287 • Status: Pågående • Ansökningsår: 2017

Grass for grazing or forage production contains variable amounts of carbohydrates, which often are described as the good (fiber), the bad (sugar) and the ugly (fructans) in relation to prevention, and development of diseases like insulin resistance and laminitis. There is a large variation in …

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Hälta eller lateralitet: när är en rörelseasymmetri betydelsefull?
Marie Rhodin, Swedish University of Agricultural Sciences

Projektnummer: H-17-47-286 • Status: Pågående • Ansökningsår: 2017

Motor laterality, such as left or right-handedness, is a well-known asymmetric phenomenon in both humans and animals, incl. horses. Concurrently, lameness caused by orthopaedic injury is a common cause for asymmetry. In our study of riding horses in training, 73 % had motion asymmetries, warranting …

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Strategier för välmående kor i lönsamma företag
Helena Hansson

Projektnummer: O-18-21-152 • Status: Pågående • Ansökningsår: 2018

Mjölk

This project aims at investigating the relationship between animal health and fertility, productivity in terms of milk yield and the economic outcome of dairy farms, and to investigate the conditions under which farms can succeed in combining profitability with high animal health standards.
There …

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Mot ett miljövänligt svenskt lantbruk
Magdalena Bieroza

Projektnummer: O-16-23-749 • Status: Pågående • Ansökningsår: 2016

Växtodling

Swedish farmers, advisors, authorities and researchers are working together towards the same goal of Zero Eutrophication by reducing losses of nutrients and sediment from agricultural land to streams, lakes and the Baltic Sea. The Focus on Phosphorus project was carried out to test measures of …

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