Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
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Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
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Status: | Pågående |
Projektnummer: | H-19-47-493 |
Kategori: | Research program | Horse |
Ansökningsår: | 2019 |
Datum för slutrapport: | 30 juni 2024 |
Huvudsökande: | Jonas Tegenfeldt |
Organisation: | Lunds Universitet |
E-postadress: | jonas.tegenfeldt@ftf.lth.se |
Telefon: | 0462228063 |
Medsökande: | Eva Tydén |
Medsökande: | null null |
All horses grazing freely are at risk of parasitic diseases. Due to a growing problem with drug resistance in parasites, there is a need to improve the diagnostic methods. One important problem with today's situation is that one diagnostic procedure costs significantly more than one treatment, both in terms of money and in working hours. Thus, there are strong driving forces to treat "just in case" rather than giving treatment only in cases where it is strictly motivated.
We therefore propose a diagnostic system based on microfluidic separation of fecal samples. The samples are treated in different steps so that the eggs of interest can be sorted and then analyzed using primarily cellular phone-based microscopy which is very easy to use for the horse owner, but also using impedance spectroscopy, and DNA analysis.
We expect our microfluidic system for the diagnosis of fecal samples is faster, easier to use, more sensitive, more accurate and less expensive than today's systems.
Alla hästar som betar fritt utsätts för risk att drabbas av parasitsjukdomar. På grund av ett växande problem med läkemedelsresistens hos parasiter finns det ett behov av att förbättra diagnostiken. Ett viktigt problem med dagens situation är att en diagnostisk analys kostar mångdubbelt mer än en behandling, såväl i reda pengar som i arbetstid. Det finns alltså starka drivkrafter att behandla ”för säkerhets skull” snarare än att behandla enbart i de fall då det är strikt motiverat.
Vi föreslår därför ett diagnossystem som baseras på mikrofluidisk separation av träckprover. Proverna behandlas i olika steg så att de ägg som är av intresse sorteras fram och sedan analyseras med främst mobiltelefonbaserad mikroskopi som är ytterst enkel att använda för den enskilde hästägaren men också med impedansspektroskopi och DNA analys.
Vi förväntar oss att vårt mikrofluidiska system för diagnos av träckprover är snabbare, enklare att använda, mer känsligt, mer precist och billigare än dagens system.
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All horses grazing freely are at risk of parasitic diseases. Due to a growing problem with drug resistance in parasites, there is a need to improve the diagnostic methods. One important problem with today's situation is that one diagnostic procedure costs significantly more than one treatment, both …
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