Stiftelsen lantbruksforskning

Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
Läs mer

Forståelse av etiologien bak acquired equine polyneuropathy via studier av Schwanske celle kulturer

Status: Pågående
Projektnummer: H-18-47-409
Kategori: Research program | Horse
Ansökningsår: 2018
Huvudsökande: siv Hanche-Olsen
Organisation: NMBU Veterinærhøgskolen
E-postadress: siv.hanche-olsen@nmbu.no
Telefon: +4767232388
Medsökande: Gjermund Gunnes
Medsökande: Gittan Gröndahl
Beviljade medel: 240 000 SEK

Acquired equine polyneuropathy (AEP) is a devastating neurologic disease affecting Nordic horses. Characteristic histopathological changes have been shown in the peripheral nerves of horses euthanized due to the disease. These include re- and demyelination as well as hypertrophy of perikaria and proteinaceous inclusions in the myelinproducing Schwann cells. The hypothesis is that an unknown factor, possibly from forage, disrupts the Schwann cell metabolism. Further studies is needed in order to elucidate the aetiology, but the availability of nervesamples is limited as they need to be sampled in immediate association with euthanasia. Transport to pathology units is mostly not feasible due to the severity of clinical signs, making collected samples very valuable. To overcome this challenge we intend to establish Schwann cell cultures, allowing freezing and thawing for further studies. The method is already established at NMBU for dogs and will be applied in affected and control horses.

Acquired equine polyneuropathy (AEP) er en dramatisk nervesykdom som rammer nordiske hester. Det er påvist karakteristiske histopatologiske forandringer i de perifere nervene på hester avlivet pga sykdommen. Disse inkluderer re- og demyelinisering, samt hypertrofi av perikaria og proteinlignende inklusjoner i de myelinproduserende Schwanske cellene. Hypotesen er at en ukjent faktor, muligens fra fôret, påvirker metabolismen i de Schwanske cellene og fremkaller forandringene. Det er nødvendig med videre studier for å kunne belyse årsaksforholdene, men begrenset tilgang på prøver har vanskeliggjort dette. Prøvene må tas ut i umiddelbar tilknytning til avlivning og mange AEP affiserte hester kan ikke transporteres til patologi-enheter. Prøver som tas ut er dermed svært verdifulle. Ved å dyrke Schwanske celler i kulturer vil dette problemet omgås fordi man kan fryse og tine dem opp igjen til videre undersøkelser. Metoden er alt etablert på NMBU for hund og vil benyttes i studien på hest.

 

Antal träffar i projektbanken: 1647

Identifiering av gener med negativ inverkan på hästens hälsa och välbefinnande: Ett ramverk baserat på helgenomsekvensering och bioinformatik på häst
Sofia Mikko, Sveriges lantbruksuniversitet

Projektnummer: H-18-47-406 • Status: Pågående • Ansökningsår: 2018

The overall aim of this project is to improve equine health and welfare by identifying causative mutations for inherited diseases to aid informed breeding of healthy horses. We will use a comparative genomics approach, combining whole-genome sequencing (WGS) and bioinformatics with state-of-the-art …

Läs mer

Hestesektoren i Norge og Sverige: Betydning for miljø, økonomi og lokalsamfunnet
Bjørn Egil Flø, Norsk institutt for bioøkonomi

Projektnummer: H-18-47-403 • Status: Pågående • Ansökningsår: 2018

This project will study the social, cultural and economic impact of the equine sector on local development. Furthermore, ti will study the land and resource use of the equine sector and how it co-exist and collaborate with other sector and other land use locally. The starting point for social and …

Läs mer

Fullständiga växthusgasbudgetar för odlade mulljordar skapar underlag för klimatsmarta åtgärder
Achim Grelle

Projektnummer: O-18-23-169 • Status: Pågående • Ansökningsår: 2018

Växtodling
Energi & biomassa
Kött
Mjölk

Conventional technology is virtually unable to measure complete GHG budgets of drained organic soils, which may provide misleading results. So, global estimates of GHG emissions are based on coarse assumptions that don’t take into account the complexity of agroecosystems. Better data are needed for …

Läs mer

Kritik, kriminalitet och hot mot svensk djurproduktion - Lantbruksföretagarnas perspektiv
Peter Lundqvist

Projektnummer: O-18-21-139 • Status: Pågående • Ansökningsår: 2018

Matfågel
Kött
Mjölk

Farmers with animal production can experience different types of criticisms directed against their activities from consumers, the media and inspecting government agencies. On another level, criminal acts are directed against the farm's activities and people on the farm, The main goal is to …

Läs mer

Hur kommer vi dit? Hållbar skörd och kvalité hos tunnel producerade jordgubbssorter
Sammar Khalil, Sveriges Lantbruksuniversitet

Projektnummer: R-18-25-147 • Status: Pågående • Ansökningsår: 2018

Strawberry is an important horticultural crop with an annual production of 566 MSEK. A higher competitiveness of the Swedish strawberry industry is paramount in order to sustain and develop it for the future. To secure high yields of good quality, superior cultivars and optimal management are …

Läs mer

Strategier för sanering av rotgall och frilevande nematoder i växtföljder med potatis och rotgrödor
Åsa Olsson Nyström

Projektnummer: O-18-20-168 • Status: Pågående • Ansökningsår: 2018

Växtodling
Potatis
Socker

Free living nematodes (FLN) and root-knot nematodes (RKN) are increasing problems in root and tuber crops such as potato, sugar beet and carrot. There is a need for effective sanitation techniques and tolerant crops/varieties to keep population levels low in the rotation. Recently, the severe …

Läs mer

Växtskydd mot sniglar och rapsjordloppor vid etablering av höstraps
Ola Lundin

Projektnummer: O-18-20-165 • Status: Pågående • Ansökningsår: 2018

Växtodling

Insufficient crop protection is an increasingly limiting factor for crop production. Damage by slugs and cabbage stem flea beetles in winter oilseed rape are timely examples of increasing crop protection problems in Sweden. We will test whether companion cropping winter oilseed rape with frost …

Läs mer

Åtgärder för att minska andelen kycklingar med Campylobacter i Sverige
Ingrid Hansson

Projektnummer: O-18-20-158 • Status: Pågående • Ansökningsår: 2018

Matfågel
Kött

The purpose of this project is to identify the transmission routes for Campylobacter to broiler flocks and recommend actions at farm level to reduce the number of chickens with Campylobacter. Furthermore, to analyse routines at slaughter including cleaning of slaughterhouses and transport crates to …

Läs mer

Fältförutsättningar för lyckad löklagring med minskat svinn
Lars Mogren, SLU

Projektnummer: R-18-25-146 • Status: Pågående • Ansökningsår: 2018

Consumers appreciate onions in all kinds of cooking. Onions can be grown in Sweden with good results. Onions can be stored for a long period. There is a potential to increase the self-sufficiency in onions. To achieve this, a better knowledge of long-term-storage potential indicator factors that …

Läs mer

Strategier för välmående kor i lönsamma företag
Helena Hansson

Projektnummer: O-18-21-152 • Status: Pågående • Ansökningsår: 2018

Mjölk

This project aims at investigating the relationship between animal health and fertility, productivity in terms of milk yield and the economic outcome of dairy farms, and to investigate the conditions under which farms can succeed in combining profitability with high animal health standards.
There …

Läs mer

Prenumerera på vårt nyhetsbrev

Namn
E-postadress