Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
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Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
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Status: | Pågående |
Projektnummer: | H-18-47-406 |
Kategori: | Research program | Horse |
Ansökningsår: | 2018 |
Huvudsökande: | Sofia Mikko |
Organisation: | Sveriges lantbruksuniversitet |
E-postadress: | Sofia.Mikko@slu.se |
Telefon: | +46-18-671979 |
Medsökande: | Tomas Bergström |
Medsökande: | null null |
The overall aim of this project is to improve equine health and welfare by identifying causative mutations for inherited diseases to aid informed breeding of healthy horses. We will use a comparative genomics approach, combining whole-genome sequencing (WGS) and bioinformatics with state-of-the-art clinical diagnosis of disease phenotypes. In the project a general framework for mutation-detection of equine monogenetic diseases will be developed. The initial focus will be on anophthalmia and microphthalmia, potentially autosomal recessive disease/s, recently observed among Swedish Warmblood horses. The objectives of the study are to:
1. clinically define monogenic diseases with autosomal recessive inheritance,
2. develop a general framework for identifying disease causing mutation with a bioinformatics pipeline for whole-genome sequencing,
3. develop a plan for breeding advise in different scenarios of inheritance patterns, and severity of the disease.
Det övergripande målet med detta projekt är att förbättra hästens hälsa och välfärd genom att identifiera orsaken till ärftliga sjukdomar och att stödja en kunskapsbaserad uppfödning av friska hästar. Vi kommer att kombinera helgenomsekvenser (WGS) och bioinformatik med kliniska diagnoser av sjukdomsfenotypen. I projektet kommer en generell “pipeline” för mutationsdetektering av monogena sjukdomar hos häst att utvecklas. Initial kommer fokus att ligga på anoftalmi och mikroftalmi, potentiellt autosomal recessiv sjukdomar, som nyligen observerats bland svenska varmblodshästar (SWB). Syftet med studien är att:
1. kliniskt definiera monogena sjukdomar med autosomalt recessivt arv,
2. utveckla en “pipeline” för att identifiera sjukdomsframkallande mutationer med bioinformatik och helgenomsekvensering,
3. Utveckla en plan för avelsrådgivning i olika scenarier av arvsmönster och svårighetsgrad av sjukdom.
Projektnummer: R-21-47-573 • Status: Pågående • Ansökningsår: 2021
Emotional instability, impulsivity, ongoing self-harm, frequent suicidal crises, interpersonal problems, substance use disorder, cognitive distortions, and severe internal pain are seen in patients with emotionally unstable personality traits. This is a patient group that requires lot of resources …
Läs merProjektnummer: H-20-47-568 • Status: Pågående • Ansökningsår: 2020
The proposed project aims to continue research for development of a vaccine protective against the pathogenic equine parasite Strongylus vulgaris. The ongoing work to establish appropriate in vitro models to screen the effect of candidate vaccine antigens/adjuvants will be continued. Cytokine …
Läs merProjektnummer: H-20-47-562 • Status: Pågående • Ansökningsår: 2020
Harness racing is hazardous as horses are running in close proximity at high speeds. Thus, an effective communication between driver and jockey-horse via rein signals to the bit is essential for safety reasons and horse welfare. However, scientific studies on rein tension in Standardbred trotters …
Läs merProjektnummer: H-20-47-566 • Status: Pågående • Ansökningsår: 2020
The overall purpose for this project is to deepen the understanding for how economic effects of the horse industry can be understood and visualised at micro level using consumption and production data in both Sweden and Norway. Background to the project is to find in the industry’s need for …
Läs merProjektnummer: JTI-20-82-485 • Status: Pågående • Ansökningsår: 2020
Poultry have a strong motivation for foraging and spend most of the day pecking and searching for food. In commercial conditions, the birds are fed a pellet diet, which is consumed very quickly. Consequently, hens spend a large part of the day engaging in abnormal non-food related pecking …
Läs merProjektnummer: JTI-20-83-497 • Status: Pågående • Ansökningsår: 2020
This application aims at finding a solution to a problem that exists in greenhouse production. Greenhouses have long been considered to be closed systems with no leakage to the surrounding environment. However, it has been shown that plant protection products (PPP) are found in the environment …
Läs merProjektnummer: JTI-20-82-491 • Status: Pågående • Ansökningsår: 2020
This project is about refining grass to meet a demand for proteins for, above all, organic poultry production and an expected increased demand for soy-free feed solutions for monogastric animals. Forage-based products also improve the economic preconditions to increase the proportion of grass in …
Läs merProjektnummer: JTI-20-82-483 • Status: Pågående • Ansökningsår: 2020
The purpose of the project is to produce reliable emission factors for storage of poultry manure regarding methane and nitrous oxide emissions.
This project will focus on methane and nitrous oxide emissions from laying hens and the project is a supplement to an FoU project funded by the Swedish …
Läs merProjektnummer: H-21-47-631 • Status: Pågående • Ansökningsår: 2021
While the equine sector in Sweden and Norway provides leisure activities, entertainment and employment for many people of all ages, these come with associated negative effects. Studies of the environmental impacts caused by the sector show that nutrient leakage from manure piles, paddocks and …
Läs merProjektnummer: O-21-20-631 • Status: Pågående • Ansökningsår: 2021
The goal with this project is to increase the profitability and production efficiency on Swedish dairy farms by renewing
the genetic evaluation of the breeding value of temperament in dairy cows. We want to investigate if automatic
recordings of behaviour using SLU Gigacow on farm level can improve …