Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
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Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
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Status: | Pågående |
Projektnummer: | H-19-47-475 |
Kategori: | Research program | Horse |
Ansökningsår: | 2019 |
Datum för slutrapport: | 30 juni 2021 |
Huvudsökande: | Amanda Raine |
Organisation: | Uppsala University |
E-postadress: | Amanda.Raine@medsci.uu.se |
Telefon: | 076-1102317 |
Medsökande: | Miia Riihimäki |
Medsökande: | null null |
Respiratory conditions is a growing issue in the equine industry and for horse welfare. Equine asthma is characterised by airway obstruction, chronic intermittent cough and mucus accumulation an impact the quality of life for affected horses. Similar to its human equivalent, equine asthma is a heterogeneous complex disease that is associated with both genetic and environmental factors. Despite extensive research the inflammatory processes underlying equine asthma remain incompletely defined. Hence, novel research strategies which lead to improved understanding of the cellular processes implicated in the disease is of importance. Here we propose to establish single cell transcriptomics for studying equine asthma at the level of individual cells and to create a comprehensive atlas of the cellular landscape in the airways of horses in health and disease. Ultimately this will lead to detection of new biomarkers, improved stratification of disease and more individualised therapy
Inflammatorisk luftvägssjukdom är en av de vanligaste orsakerna till nedsatt prestation hos hästar. Hästens astma karaktäriseras av varierande grad av återkommande hosta, andningsvårigheter och ökad slemproduktion i luftvägarna och påverkar hästens livskvalitet. I likhet med human astma är hästens astma en heterogen och komplex sjukdom som kan associeras med både miljöfaktorer och genetiska faktorer. Trots omfattande forskning så är faktorerna bakom hästens astma till stora delar okänd. Det är därför önskvärt med nya metoder och strategier för att fördjupa kunskapen om de sjukdomspecifika cellulära och inflammatoriska processerna. I detta projekt ska vi använda transkriptomanalys i enskilda celler för att karaktärisera celler i luftvägarna hos hästar diagnostiserade med astma. Förhoppningen är att denna metod ska kunna användas som ett verktyg för att finna biomarkörer, förbättra sjukdomsklassificering och i förlängningen leda till mer individualiserad behandling.
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The aim of this project is to investigate individual differences in the rate of passage of feed, feed efficiency, microbial flora and methane production in cows with different ability to consume large proportion of roughage.
Our previous studies show that methane production differs between cows …
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This project is the Swedish part of the Nordic 4-year project Improving Nordic dairy cow fertility through genetics, the only prioritized research project from Nordic Dairy Cattle R&D, 2015. Research funding is applied for within each country. The focus area of our Swedish part is to investigate …
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A primary reason for unhealthy legs and claws are unsuitable floor properties in dairy houses,
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Projektnummer: H-19-47-475 • Status: Pågående • Ansökningsår: 2019
Respiratory conditions is a growing issue in the equine industry and for horse welfare. Equine asthma is characterised by airway obstruction, chronic intermittent cough and mucus accumulation an impact the quality of life for affected horses. Similar to its human equivalent, equine asthma is a …
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The project aims to develop a decision support tool to aid farmers when investing in precision agriculture technology. The project will develop a model to assess the profitability of investments in precision agriculture technology. Within the project data from Swedish and international field trials …
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Knowledge of disease development in wheat is a prerequisite for good advice on economically and environmentally
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The purpose of the project is to analyse stable cultures in cyberspace in Sweden and Norway. In recent years, questions about the welfare of horses have been debated in social media and norms for horse-keeping are created on Internet. In this project, these norms are conceptualised as stable …
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We aim to continue an ongoing study to increase knowledge of cattle locomotion on different floors, how they work in practice and what the long term consequences are for welfare and for farmers´ economy. For that purpose advanced biomechanical methods will be used to assess dairy cows´ …
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