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Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
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Status: | Pågående |
Projektnummer: | H-18-47-390 |
Kategori: | Research program | Horse |
Ansökningsår: | 2018 |
Huvudsökande: | Johan Bröjer |
Organisation: | SLU |
E-postadress: | johan.brojer@slu.se |
Telefon: | 018-671388 |
Medsökande: | Sanna Truelsen Lindåse |
Medsökande: | null null |
Laminitis, an extremely painful disease of the equine foot, is most commonly caused by elevated insulin
concentrations in blood (hyperinsulinemia). Therefore, strategies to reduce hyperinsulinemia in horses are warranted.
Studies in obese children with insulin dysregulation and hyperinsulinemia have identified elevated levels of the
hormone glucagon in blood. To identify novel treatment strategies for preventing laminitis we compared insulin
dysregulation in the horse with that observed in humans. We found that horses with insulin dysregulation also had an
excessive glucagon secretion during an oral sugar test in a small pilot study.
If the results of the pilot study hold true also for a larger population of horses, this would be a breakthrough in the
understanding of the pathophysiology of insulin dysregulation in the horse. This opens up for medical treatment of
these horses since there are treatment strategies for an abnormal glucagon response in humans with -cell
dysregulation.
Fång, en smärtsam sjukdom som drabbas hästens hov, orsakas i de flesta fall av förhöjda koncentrationer av insulin i
blodet (hyperinsulinemi). På grund av detta samband finns det ett stort behov av att finna metoder, som minskar
graden av hyperinsulinemi hos häst.Studier utförda på överviktiga barn med störd insulinmetabolism och hyperinsulinemi har funnit förhöjda nivåer av hormonet glukagon i blodet. I likhet med dessa resultat har vår forskargrupp i en mindre pilotstudie visat att hästar med hyperinsulinemi också hade en ökad frisättning av glukagon under ett oralt glukostoleranstest.
Om vi studerar detta samband i en större hästpopulation och då påvisar samma resultat som i pilotstudien, skulle det
innebära ett stor genombrott i förståelsen om hur hyperinsulinemi uppstår hos häst. Det skulle innebära att nya
behandlingsmetoder mot hyperinsulinemi hos häst blir tillgängliga, då det redan finns behandlingsstrategier med
läkemedel vid störd glukagonmetabolism hos människa.
Projektnummer: H-18-47-401 • Status: Pågående • Ansökningsår: 2018
The goal of the applied project is to shed light on overlooked aspects of the complex subject of horse welfare.
Because of the specific position stall owners have, they are especially suitable to contribute to our knowledge about
the possibilities and limitations that set the conditions for …
Projektnummer: O-16-23-749 • Status: Pågående • Ansökningsår: 2016
Swedish farmers, advisors, authorities and researchers are working together towards the same goal of Zero Eutrophication by reducing losses of nutrients and sediment from agricultural land to streams, lakes and the Baltic Sea. The Focus on Phosphorus project was carried out to test measures of …
Läs merProjektnummer: R-18-25-022 • Status: Pågående • Ansökningsår: 2018
The root-knot nematode, Meloidogyne hapla, is an increasing problem in carrot cultivation in Sweden and Europe. Soil analysis is extremely important to plan sustainable crop rotations, reduce nematode multiplication in soil and eventually minimize yield loss. Traditional soil analyses are time …
Läs merProjektnummer: R-18-26-129 • Status: Pågående • Ansökningsår: 2018
Improved feed efficiency (FE) is a key parameter for increased sustainability in modern diary production. The project aims to increase the efficiency of converting feed into milk and reducing the environmental impact of dairy production. In order for farmers and breeding companies to include FE as …
Läs merProjektnummer: R-18-26-133 • Status: Pågående • Ansökningsår: 2018
Food is a central component for a sustainable society, environmentally but also for public health. To make sound decisions on sustainable food choices, methods that combine environmental impact, nutritional supply and health impacts need to be developed. Currently, evidence based methods for such …
Läs merProjektnummer: R-18-26-131 • Status: Pågående • Ansökningsår: 2018
In the proposed project, we will explore the benefits of increasing the longevity of dairy cows under Swedish conditions by changes in herd management. We will focus on effects on methane emissions by modelling, using existing data from the Swedish Official Milk Recording Scheme and results from an …
Läs merProjektnummer: R-18-26-136 • Status: Pågående • Ansökningsår: 2018
Sustainable dairy systems must strive for practices that reduce the negative impacts and enhance the positive impacts, and find measures to track changes in relation to different goals. The aim of this project is to investigate how indicators and tools for ecosystem services and biodiversity can be …
Läs merProjektnummer: R-18-25-143 • Status: Pågående • Ansökningsår: 2018
Green house production depends or reliable substrates and fertilizers. Peat is the dominating substrate in Sweden and internationally. There is a debate about reducing the peat use since the mining for peat may increase climate gas emissions and disturb sensitive ecosystems. Thus, alternative for …
Läs merProjektnummer: H-15-47-097 • Status: Pågående • Ansökningsår: 2015
Development of resistance to anthelmintics is a threat to equine welfare. As with antibiotics, restrictive use with anthelmintics in order to retain the effect is essential. Current recommendation for deworming is targeted selective treatment to individuals shedding a certain amount of parasite …
Läs merProjektnummer: H-15-47-063 • Status: Pågående • Ansökningsår: 2015
The purpose is to examine haylage 'intolerance' in horses, which is expressed as diarrhoeic faeces in some horses when they are fed haylage (sometimes also when fed hay). A typical appearance is two-phase faeces - one solid and one liquid. It is not known why or how this condition appears, and it …
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