Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
Läs mer
Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
Läs mer
Status: | Pågående |
Projektnummer: | H-18-47-390 |
Kategori: | Research program | Horse |
Ansökningsår: | 2018 |
Huvudsökande: | Johan Bröjer |
Organisation: | SLU |
E-postadress: | johan.brojer@slu.se |
Telefon: | 018-671388 |
Medsökande: | Sanna Truelsen Lindåse |
Medsökande: | null null |
Laminitis, an extremely painful disease of the equine foot, is most commonly caused by elevated insulin
concentrations in blood (hyperinsulinemia). Therefore, strategies to reduce hyperinsulinemia in horses are warranted.
Studies in obese children with insulin dysregulation and hyperinsulinemia have identified elevated levels of the
hormone glucagon in blood. To identify novel treatment strategies for preventing laminitis we compared insulin
dysregulation in the horse with that observed in humans. We found that horses with insulin dysregulation also had an
excessive glucagon secretion during an oral sugar test in a small pilot study.
If the results of the pilot study hold true also for a larger population of horses, this would be a breakthrough in the
understanding of the pathophysiology of insulin dysregulation in the horse. This opens up for medical treatment of
these horses since there are treatment strategies for an abnormal glucagon response in humans with -cell
dysregulation.
Fång, en smärtsam sjukdom som drabbas hästens hov, orsakas i de flesta fall av förhöjda koncentrationer av insulin i
blodet (hyperinsulinemi). På grund av detta samband finns det ett stort behov av att finna metoder, som minskar
graden av hyperinsulinemi hos häst.Studier utförda på överviktiga barn med störd insulinmetabolism och hyperinsulinemi har funnit förhöjda nivåer av hormonet glukagon i blodet. I likhet med dessa resultat har vår forskargrupp i en mindre pilotstudie visat att hästar med hyperinsulinemi också hade en ökad frisättning av glukagon under ett oralt glukostoleranstest.
Om vi studerar detta samband i en större hästpopulation och då påvisar samma resultat som i pilotstudien, skulle det
innebära ett stor genombrott i förståelsen om hur hyperinsulinemi uppstår hos häst. Det skulle innebära att nya
behandlingsmetoder mot hyperinsulinemi hos häst blir tillgängliga, då det redan finns behandlingsstrategier med
läkemedel vid störd glukagonmetabolism hos människa.
Projektnummer: R-18-25-147 • Status: Pågående • Ansökningsår: 2018
Strawberry is an important horticultural crop with an annual production of 566 MSEK. A higher competitiveness of the Swedish strawberry industry is paramount in order to sustain and develop it for the future. To secure high yields of good quality, superior cultivars and optimal management are …
Läs merProjektnummer: O-18-20-165 • Status: Pågående • Ansökningsår: 2018
Insufficient crop protection is an increasingly limiting factor for crop production. Damage by slugs and cabbage stem flea beetles in winter oilseed rape are timely examples of increasing crop protection problems in Sweden. We will test whether companion cropping winter oilseed rape with frost …
Läs merProjektnummer: O-18-20-175 • Status: Pågående • Ansökningsår: 2018
The project aims to lay the foundation for genomic selection in Swedish beef cattle populations. Genomic selection has revolutionized animal breeding and much increased genetic progress in e.g. dairy cattle. Improved animal breeding increases production efficiency and genomic selection enables …
Läs merProjektnummer: H-15-47-097 • Status: Pågående • Ansökningsår: 2015
Development of resistance to anthelmintics is a threat to equine welfare. As with antibiotics, restrictive use with anthelmintics in order to retain the effect is essential. Current recommendation for deworming is targeted selective treatment to individuals shedding a certain amount of parasite …
Läs merProjektnummer: JTI-19-82-291 • Status: Pågående • Ansökningsår: 2019
Applying circular economy principles to agriculture is a systematic approach to reduce the environmental and climate impact of agriculture while increasing efficiency, production and profitability. The road to circular agriculture requires that we 1) minimize external inputs, 2) reduce losses and …
Läs merProjektnummer: R-19-25-282 • Status: Pågående • Ansökningsår: 2019
Potato cultivars that are resistant to late blight and at the same time having acceptable other traits, have started to emerge. However, little of this material is used in Sweden and no organized and comparative table potato trials are done. Biological products against skin-finish diseases are …
Läs merProjektnummer: R-19-25-287 • Status: Pågående • Ansökningsår: 2019
The purpose of this project is to develop new non-chemical methods for control of different seedborne-and soilborne pathogens. Aerated steam treatment (ThermoSeed) is a modern and environmentally friendly method for seedborne pathogen sanitation, mainly used on cereals. We intend to develop the …
Läs merProjektnummer: R-20-62-325 • Status: Pågående • Ansökningsår: 2020
This project is connected to an already funded grazing application from Norway intending to evaluate methane production from dairy cows in different grazing systems. We aim to evaluate further some important aspects of grazing in northern Sweden. We plan to use some sensory techniques to analyse …
Läs merProjektnummer: R-20-62-327 • Status: Pågående • Ansökningsår: 2020
More and more consumers desire a tasty meat where production have considered the environmental impact and animal welfare. The purpose of this interdisciplinary project is to determine how to produce such a product while still make the production profitable, climate efficient and otherwise …
Läs merProjektnummer: R-20-62-324 • Status: Pågående • Ansökningsår: 2020
Agriculture in plain-lands is often specialized in crop production, with no on-farm use of ley as animal fodder, and crop rotations that often includes only annual crops (e.g. oilseed rape, cereals and sugar beets). At the same time, integrating ley in arable cropping systems generates several …
Läs mer