Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
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Lantbruks- och trädgårdsföretagarnas egen forskningsstiftelse finansierar behovsdriven forskning för svenska förhållanden.
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Status: | Pågående |
Projektnummer: | H-21-47-649 |
Kategori: | Research program | Horse |
Ansökningsår: | 2021 |
Huvudsökande: | Malin Connysson |
Organisation: | Wången AB |
E-postadress: | malin.connysson@wangen.se |
Telefon: | 0640-17431 |
Medsökande: | Anna Jansson |
Medsökande: | null null |
It is generally accepted that muscle enzyme activity (CK and AST) levels in plasma may increase in Standardbreds and Thoroughbreds after exercise and racing, indicating muscle damage. However, in one recent study on healthy Standardbred trotters fed a forage only diet muscle enzyme activity levels were very low after race-like exercise tests. Interestingly, lowered muscle enzyme responses after exercise has also been observed in horses with recurrent exertional rhabdomyolysis as well as in healthy athletic horses when feed low starch diets So, could it be that it is the diet and not the exercise that is causing muscle damage and enzyme leakage? The aim of the project is to evaluate the effect of different energy substrate intakes on plasma muscle enzyme activity post exercise. The hypothesis is that the plasma muscle enzyme activity levels considered normal for athletic horses are highly dependent on starch rich diets and to a lesser degree dependent on exercise.
Det är allmänt accepterat att nivåerna av muskelenzymaktivitet (CK och AST) i plasma kan öka hos travhästar och fullblod efter träning och tävling, vilket indikerar muskelskador. I en nyligen genomförd studie på friska travhästar, som utfodrats med en grovfoderdiet, var dock muskelenzym-nivåerna i plasma mycket låga efter ett tävlingsliknande arbetstest. Ett lägre muskelenzymsvar efter träning har också observerats hos hästar med återkommande korsförlamning såväl som hos friska galopphästar när de utfodrades med foder med låga stärkelsenivåer. Det här väcker frågan, kan det vara så att det är fodret och inte träningen som orsakar muskelskador och enzymläckage? Syftet med projektet är att utvärdera effekten av olika energisubstrat på plasmakoncentrationerna av muskelenzym efter träning. Hypotesen är att de plasmakoncentrationer av CK och AST som anses normala för kapplöpningshästar i stor utsträckning beror på stärkelserika dieter och i mindre grad beror på träning och tävling.
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